
02.02.2016
Maternal blood Y chromosome gene detection
Y-Chromosome DNA Test
In the 1970’s scientists discovered that fetal DNA passes through the placenta and enters the maternal blood circulatory system in the form of fetal metabolites or fetal DNA fragments. Experts point out that, the longer the fetus stays in the womb, the more concentrated the fetal DNA fragments will be in the maternal blood. In addition, the faster the diffusion process, the more fetal DNA fragments will be found in the maternal blood.
To summarize, a longer gestation period and faster diffusion process, results in more fetal DNA fragments in the maternal circulatory system. Nowadays, fetal sex can be determined through the application of advanced maternal blood DNA testing technology as early as 5 gestation weeks. The test involves isolating the fetal DNA fragments from the maternal serum, and then extracting and amplifying them. Once millions or possibly billions of copies have been made, the male DNA will be tested with the Sex-determining Region Y (SRY) markers.
In males, Y DNA is the genetic material that is inherited from the father only, which is crucial material for the fetus to develop as a male. Since Y DNA is inherited from the father and then passed on to the son, it can be used in paternity confirmation by simple comparison.
Test Details
Code | Test | Sample format | TAT (working day) |
YCHR5 | Y-chromosome maternal serum test (5 weeks) | 8.5mL CEL-Free BCT x 1 | 1 |
YCHR6 | Y-chromosome maternal serum test (6 weeks) | 8.5mL CEL-Free BCT x 1 | 1 |
YCHR | Y-chromosome maternal serum test (7 weeks) | 8.5mL CEL-Free BCT x 1 | 1 |
Test Features
1. No Fasting is required
2. Non-invasive, inflicting minimal harm to the fetus
3. Unaffected by medication or body condition
4. High sensitivity, a tiny amount of fetal Y-DNA can be detected precisely
5. High accuracy, >99.99%
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